BDBM209910 US9273014, Comparative Compound 46::US9427442, Comparative Compound 27
SMILES CC(C)C[C@H]([C@H](CC=C)C(N)=O)C(=O)N[C@H]1N=C(c2ccccc2)c2cc(Cl)ccc2N(C)C1=O
InChI Key InChIKey=NFSUDFPUVQNBSA-WZOHSFFVSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 209910
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 42.4nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 3/Recombining binding protein suppressor of hairless(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 74.5nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 1/Recombining binding protein suppressor of hairless(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 42.4nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair
TargetNeurogenic locus notch homolog protein 3/Recombining binding protein suppressor of hairless(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 74.5nMAssay Description:The Notch-CBF1 (C-promoter binding factor I) cell based transactivation assay is based on the ability of the released Notch intracellular domain frag...More data for this Ligand-Target Pair