BDBM209925 PKUMDL-WQ-2201
SMILES CCNC(=S)N\N=C/c1ccc(o1)-c1ccc(C(O)=O)c(Cl)c1
InChI Key InChIKey=XPACBFAEZIPDRT-LSCVHKIXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 209925
Affinity DataIC50: 3.57E+4nMpH: 7.1Assay Description:To evaluate the effects of compounds on PHGDH activity, compounds were first pre-incubated with enzyme samples in the assay buffer (25 mM HEPES, pH 7...More data for this Ligand-Target Pair
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of human full-length PHGDH incubated for 10 mins by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 6.69E+4nMpH: 7.4Assay Description:The binding affinities of compounds towards PHGDH were assayed using the SPR-based Biacore T200 instrument (GE Healthcare). PHGDH was immobilized on ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMpH: 7.1Assay Description:To evaluate the effects of compounds on PHGDH activity, compounds were first pre-incubated with enzyme samples in the assay buffer (25 mM HEPES, pH 7...More data for this Ligand-Target Pair