BDBM209925 PKUMDL-WQ-2201

SMILES CCNC(=S)N\N=C/c1ccc(o1)-c1ccc(C(O)=O)c(Cl)c1

InChI Key InChIKey=XPACBFAEZIPDRT-LSCVHKIXSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 209925   

TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM209925(PKUMDL-WQ-2201)
Affinity DataIC50:  3.57E+4nMpH: 7.1Assay Description:To evaluate the effects of compounds on PHGDH activity, compounds were first pre-incubated with enzyme samples in the assay buffer (25 mM HEPES, pH 7...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM209925(PKUMDL-WQ-2201)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of human full-length PHGDH incubated for 10 mins by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Peking University

LigandPNGBDBM209925(PKUMDL-WQ-2201)
Affinity DataKd:  6.69E+4nMpH: 7.4Assay Description:The binding affinities of compounds towards PHGDH were assayed using the SPR-based Biacore T200 instrument (GE Healthcare). PHGDH was immobilized on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase [3-314](Homo sapiens (Human))
Peking University

LigandPNGBDBM209925(PKUMDL-WQ-2201)
Affinity DataIC50:  3.50E+4nMpH: 7.1Assay Description:To evaluate the effects of compounds on PHGDH activity, compounds were first pre-incubated with enzyme samples in the assay buffer (25 mM HEPES, pH 7...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed