BDBM21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin

SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO

InChI Key InChIKey=HPZJMUBDEAMBFI-WTNAPCKOSA-N

Data  137 KI  32 IC50  9 Kd  97 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21015   

TargetDelta-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  1.53E+3nMAssay Description:Displacement of [125I]-Deltorphin 2 from mouse Flag-tagged delta-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]-DAMGO from mouse Flag-tagged mu-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  28nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced contractionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  950nMAssay Description:Agonist activity at delta-opioid receptor in mouse vasa deferens assessed as inhibition of electrically induced contractionsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  0.260nMAssay Description:Tested for thromboxane antagonist potency (pA2) against U 44619 induced platelet aggregation using human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  49nMAssay Description:Tested for thromboxane antagonist potency (pA2) against U 44619 induced platelet aggregation using human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed