BDBM210756 US9290454, 4.1

SMILES C[C@@H]1CN(CCN1C(=O)c1ccc2c(cc(CCCCC(O)=O)n(-c3ccc(F)cc3)c2=O)c1)c1ccc(F)cc1

InChI Key InChIKey=YTMWEJHKTHDECR-OAQYLSRUSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210756   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM210756(US9290454, 4.1)
Affinity DataKi:  22.5nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding was performed using filtration or scintillation proximity assay (SPA) technology. SPA assays were done at room temperature in 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM210756(US9290454, 4.1)
Affinity DataKi:  24nMAssay Description:Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed