BDBM210853 US9290467, 23
SMILES FC(F)(F)c1ccc2c(OCCCCOc3ccc(C[C@H](NC2=O)C(=O)NC2(CC2)C#N)cc3Cl)c1
InChI Key InChIKey=XAPRSGPLBWSEHV-IBGZPJMESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 210853
Affinity DataKi: 10nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using AMMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using MFC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using DBF as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair