BDBM210903 US9273043, A158(a)

SMILES C[C@H]1CN(CCN1C(=O)Nc1nc2cc(F)c(F)cc2s1)c1ncc(cc1F)[C@H](O)CO

InChI Key InChIKey=PLPNXVMXQNODJV-MGPLVRAMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210903   

LigandPNGBDBM210903(US9273043, A158(a))
Affinity DataIC50:  17.1nMpH: 7.2 T: 37°CAssay Description:pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM210903(US9273043, A158(a))
Affinity DataIC50:  62.4nMpH: 7.4Assay Description:One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent