BDBM21121 (2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(1R)-1-[({[(2S)-1-oxo-3-phenyl-1-[4-(N-phenylpropanamido)piperidin-1-yl]propan-2-yl]carbamoyl}methyl)carbamoyl]ethyl]propanamide::4-anilidopiperidine, 16

SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1

InChI Key InChIKey=XEGINLDCVLRGAF-KUSJRIKGSA-N

Data  5 KI  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 21121   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataKi:  0.360nM ΔG°:  -12.9kcal/mole EC50:  0.770nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataKi:  0.380nM ΔG°:  -12.8kcal/mole EC50:  0.880nMpH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataIC50:  8.5nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataIC50:  1.80nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataEC50:  0.770nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM21121((2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(...)
Affinity DataEC50:  0.880nMAssay Description:Agonist activity at rat mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed