BDBM211262 US9247759, 10-10

SMILES Cc1noc(C)c1Cn1cc(cn1)N1C(=O)CN(Cc2cccc(O)c2)C1=O

InChI Key InChIKey=LLJBKECMPVCSDS-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 211262   

TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Senomyx

US Patent
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataIC50:  35nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Senomyx

US Patent
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataIC50:  30nMAssay Description:To determine the effectiveness of an individual antagonist, taste tests were performed with a T2R8 specific agonist, the compound of interest and a r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTaste receptor type 2 member 8(Homo sapiens (Human))
Senomyx

US Patent
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 14(Homo sapiens (Human))
Firmenich

Curated by ChEMBL
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at TAS2R14 (unknown origin) by stably expressed cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTaste receptor type 2 member 1(Homo sapiens)
Firmenich

Curated by ChEMBL
LigandPNGBDBM211262(US9247759, 10-10)
Affinity DataEC50:  1.50E+5nMAssay Description:Agonist activity at TAS2R1 (unknown origin) by stably expressed cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed