BDBM211262 US9247759, 10-10
SMILES Cc1noc(C)c1Cn1cc(cn1)N1C(=O)CN(Cc2cccc(O)c2)C1=O
InChI Key InChIKey=LLJBKECMPVCSDS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 211262
Affinity DataIC50: 35nMAssay Description:In another embodiment, Fluorescence Polarization ("FP") based assays may be used to detect and monitor ligand binding. Fluorescence polarization is a...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:To determine the effectiveness of an individual antagonist, taste tests were performed with a T2R8 specific agonist, the compound of interest and a r...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at recombinant human TAS2R8 stably expressed in cells co-expressing Galpha16gust44 assessed as inhibition of andrographolide-indu...More data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Agonist activity at TAS2R14 (unknown origin) by stably expressed cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+5nMAssay Description:Agonist activity at TAS2R1 (unknown origin) by stably expressed cell-based assayMore data for this Ligand-Target Pair