BDBM213234 Phen-DC6

SMILES C[n+]1cccc2cc(NC(=O)c3ccc4ccc5ccc(nc5c4n3)C(=O)Nc3ccc4[n+](C)cccc4c3)ccc12

InChI Key InChIKey=CPGLBMNDOCLYCG-UHFFFAOYSA-P

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 213234   

TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  174nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  120nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  55nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent DNA helicase DinG(Escherichia coli (Enterobacteria))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  60nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFanconi anemia group J protein(Homo sapiens (Human))
National Institutes of Health, National Institutes of Health Biomedical Research Center

LigandPNGBDBM213234(Phen-DC6)
Affinity DataIC50:  0.130nMpH: 8.0Assay Description:Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed