BDBM21335 6-cyanouridine 5-monophosphate::C6-Uridine Derivative, 6::JMC521648 Compound 34::{[(2R,3S,4R,5R)-5-(6-cyano-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

SMILES O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1c(cc(=O)[nH]c1=O)C#N

InChI Key InChIKey=GCVKNFUDFHDSJQ-ZOQUXTDFSA-N

Data  5 KI

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 21335   

TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.60E+4nM ΔG°:  -6.50kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.90E+4nM ΔG°:  -6.81kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase at 55 degreeC by competitive binding assayMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.90E+4nM ΔG°:  -6.81kcal/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  6.20E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed