BDBM2144 1-(5-chloropyridin-2-yl)-3-{2-[4-(dimethylamino)-2,6-difluorophenyl]ethyl}thiourea::LY300046HCl Analog 30::N-[2-(2,6-Difluoro-4-(dimethylamino)phenethyl)]-N-[2-(5-chloropyridyl)]thiourea::PETT deriv.
SMILES CN(C)c1cc(F)c(CCNC(=S)Nc2ccc(Cl)cn2)c(F)c1
InChI Key InChIKey=CTKOUWBTBJGZKA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2144
Affinity DataIC50: 20nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 270nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair