BDBM214697 US9296728, 19
SMILES COc1cc(ccc1\C=C(/C#N)C(O)=O)N(Cc1ccccc1)Cc1ccccc1
InChI Key InChIKey=VOPFDHPGYLVCCO-HYARGMPZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 214697
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents of The University of Minnesota
US Patent
Regents of The University of Minnesota
US Patent
Affinity DataIC50: 19nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of MCT4 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of MCT1 (unknown origin) assessed as reduction in [14C]lactate uptake incubated for 20 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair