BDBM214701 US9296728, 24

SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(CC#C)CC#C

InChI Key InChIKey=UDBJVBGONKDLFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 214701   

TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM214701(US9296728, 24)
Affinity DataIC50:  210nMAssay Description:Inhibition of MCT1 in rat brain endothelial 4 cells assessed as L-[14C]-Lactate Uptake after 15 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM214701(US9296728, 24)
Affinity DataIC50:  150nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent