BDBM21493 2-chloro-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]pyrazol-3-yl]quinoline::Dihydropyrrolopyrazole, 7b

SMILES Clc1cc(-c2c3CCCn3nc2-c2ccccn2)c2ccccc2n1

InChI Key InChIKey=LAVVISXEUOZAMM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21493   

TargetTGF-beta receptor type-1 [4-503,T204D](Homo sapiens (Human))
Eli Lilly

LigandPNGBDBM21493(2-chloro-4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-...)
Affinity DataIC50:  1.98E+4nM EC50: >2.00E+4nMpH: 7.5 T: 2°CAssay Description:The kinase activity was assayed by the autophosphorylation reaction of ALK5 (T204D) in the presence of 4 uM ATP and [33P]-gamma-ATP. After incubation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed