BDBM2154 1-(5-bromopyridin-2-yl)-3-[2-(5,6-dimethyl-2H-1,2,3-benzotriazol-2-yl)ethyl]thiourea::LY300046HCl Analog 40::N-[2-(5,6-Dimethylbenzotriazol-2-yl)ethyl]-N-[2-(5-bromopyridyl)]thiourea::PETT deriv.
SMILES Cc1cc2nn(CCNC(=S)Nc3ccc(Br)cn3)nc2cc1C
InChI Key InChIKey=VHHBIUGQQVIUQZ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2154
Affinity DataIC50: 150nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 100nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: >2.50E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair