BDBM2157 3-[2-(2-chloro-3-ethoxy-6-fluorophenyl)ethyl]-1-(5-chloropyridin-2-yl)thiourea::LY300046HCl Analog 11::N-[2-(2-Chloro-3-ethoxy-6-fluorophenethyl)]-N-[2-(5-chloropyridyl)]thiourea::PETT deriv.
SMILES CCOc1ccc(F)c(CCNC(=S)Nc2ccc(Cl)cn2)c1Cl
InChI Key InChIKey=NIINQTIUVDCATJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 2157
Affinity DataIC50: 6nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 30nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
Eli Lilly
Eli Lilly
Affinity DataIC50: 130nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair