BDBM21659 (2S)-3-(1H-indol-3-yl)-2-[(2R)-3-sulfanyl-2-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]propanamido]propanoic acid::Mercaptoacyl amino acid compound, 14d

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CS)[C@@H]1CCCc2ccccc12

InChI Key InChIKey=NEVHGNNWXYABCA-SJBKTWHCSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21659   

TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Cnrs

LigandPNGBDBM21659((2S)-3-(1H-indol-3-yl)-2-[(2R)-3-sulfanyl-2-[(1S)-...)
Affinity DataKi:  43nM ΔG°:  -10.4kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed