BDBM21709 2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2-yl)carbonyl]pyrrolidin-3-yl]-1H-1,3-benzodiazole::benzimidazole, 18

SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1nc2ccc(OC)cc2[nH]1

InChI Key InChIKey=VTSVIVIZRMTHNK-CQSZACIVSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 21709   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataEC50:  1.87E+3nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50:  4.20E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandPNGBDBM21709(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Affinity DataIC50:  970nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed