BDBM21851 2-benzyl-1'-[4-(propan-2-yl)cyclohexyl]-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-3-one::Piperidine Derivative, 5p

SMILES CC(C)C1CCC(CC1)N1CCC2(CC1)C(=O)N(Cc1ccccc1)Cc1ccccc21

InChI Key InChIKey=KUSRIKGAPXLENN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21851   

TargetNociceptin receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21851(2-benzyl-1'-[4-(propan-2-yl)cyclohexyl]-2,3-dihydr...)
Affinity DataKi:  6.60nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21851(2-benzyl-1'-[4-(propan-2-yl)cyclohexyl]-2,3-dihydr...)
Affinity DataKi:  928nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21851(2-benzyl-1'-[4-(propan-2-yl)cyclohexyl]-2,3-dihydr...)
Affinity DataKi:  1.34E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Istituto Superiore Di Sanita

LigandPNGBDBM21851(2-benzyl-1'-[4-(propan-2-yl)cyclohexyl]-2,3-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed