BDBM218675 US9290501, PT-ImmH

SMILES OC1[C@@H](CSc2ccccc2)NC(Cc2c[nH]c3c2nc[nH]c3=O)C1O

InChI Key InChIKey=QAVYACWIWJFJQI-NZJPAHGCSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218675   

TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College of Medicine

US Patent
LigandPNGBDBM218675(US9290501, PT-ImmH)
Affinity DataKi:  0.0350nM ΔG°:  -14.3kcal/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College of Medicine

US Patent
LigandPNGBDBM218675(US9290501, PT-ImmH)
Affinity DataKi:  0.660nM ΔG°:  -12.5kcal/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent