BDBM21993 6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]-N-methoxy-N,3-dimethyl-1-(2-methylpropyl)-2,4-dioxo-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-5-carboxamide::Thienopyrimidine-2,4-dione, 8

SMILES CON(C)C(=O)c1c(Cn2c(C)nc(Cl)c2Cl)sc2n(CC(C)C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=CMLJYPLKIKPWDF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21993   

TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21993(6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...)
Affinity DataKi:  3.20nM ΔG°:  -11.5kcal/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM21993(6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed