BDBM220121 US9271961, Cloxazolam

SMILES Clc1ccc2NC(=O)CN3CCOC3(c3ccccc3Cl)c2c1

InChI Key InChIKey=ZIXNZOBDFKSQTC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220121   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)
Affinity DataKi:  1.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent