BDBM221243 US9303015, 17
SMILES COc1ccc(cn1)C(O)(c1cncn1C)c1ccc2nc(N(C)C)c(Oc3ccccc3)c(Cl)c2c1
InChI Key InChIKey=TZZKHOLXWCJBLK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 221243
TargetNuclear receptor ROR-gamma [258-518,Y502F](Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Janssen Pharmaceutica
US Patent
Affinity DataIC50: 150nMAssay Description:The reporter assay was performed by transiently transfecting HEK293T cells with 5 μg of pBIND-RORγt LBD or pBIND-RORγt LBD-AF2 and 5 &...More data for this Ligand-Target Pair
Affinity DataKd: 4.10nMpH: 7.0 T: 2°CAssay Description:ThermoFluor® experiments were carried out using instruments owned by Janssen Research and Discovery, L.L.C. through its acquisition of 3-Dimensio...More data for this Ligand-Target Pair