BDBM221694 US10568884, Cpd 15::US9314464, 15::US9593100, Compound 15::USRE49556, Compound 15
SMILES COC(=O)N[C@@H](C)CNc1nccc(n1)-c1cn(nc1-c1cc(F)cc(NS(C)(=O)=O)c1Cl)C(C)C
InChI Key InChIKey=ZKZGAMDUVHYNPH-ZDUSSCGKSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 221694
Affinity DataIC50: 1.10nMAssay Description:B-Raf (V600E; 4 pM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgC...More data for this Ligand-Target Pair