BDBM221707 US10568884, Cpd 28::US9314464, 28::US9593100, Compound 28::USRE49556, Compound 28

SMILES CC(C)n1cc(c(n1)-c1cc(Cl)cc(NS(C)(=O)=O)c1F)-c1ccnc(NCCN(C)C)n1

InChI Key InChIKey=XHBPQUQPPQNMMJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221707   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM221707(US10568884, Cpd 28 | US9314464, 28 | US9593100, Co...)
Affinity DataIC50:  90nMAssay Description:B-Raf (V600E; 4 pM) and biotinylated Mek (kinase dead; 10 nM) were combined at 2× final concentrations in assay buffer (50 mM Tris, pH 7.5, 15 mM MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent