BDBM22205 1,2,4-oxadiazole based compound, 22::1-[(4-{5-[4-(2-methylbutan-2-yl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)methyl]azetidine-3-carboxylic acid

SMILES CCC(C)(C)c1ccc(cc1)-c1nc(no1)-c1ccc(CN2CC(C2)C(O)=O)cc1

InChI Key InChIKey=ZQHLJZUCUJZZRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22205   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22205(1,2,4-oxadiazole based compound, 22 | 1-[(4-{5-[4-...)
Affinity DataIC50:  1.30nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22205(1,2,4-oxadiazole based compound, 22 | 1-[(4-{5-[4-...)
Affinity DataIC50:  1.80nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22205(1,2,4-oxadiazole based compound, 22 | 1-[(4-{5-[4-...)
Affinity DataIC50:  75nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM22205(1,2,4-oxadiazole based compound, 22 | 1-[(4-{5-[4-...)
Affinity DataIC50:  3.09E+3nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed