BDBM222077 6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]pyridin-8-yl)methoxy)-[1,2,4]triazolo[4,3-b] pyridazine (7e)

SMILES Clc1ccc(Cl)c(c1)-c1cn2cccc(COc3nnc4ccc(Cl)nn34)c2n1

InChI Key InChIKey=VWLARPQJDBXNHQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222077   

TargetEpidermal/Hepatocyte growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50:  1.56E+4nMAssay Description:The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor/Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50:  1.23E+4nMAssay Description:The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase/Hepatocyte growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM222077(6-chloro-3-((2-(2,5-dichlorophenyl)imidazo[1,2-a]p...)
Affinity DataIC50:  1.35E+4nMAssay Description:The c-Met kinase activity as tested with enzyme-linked immunosorbent assays (ELISAs) as previously reported protocol [Qiang et al., Bioorg. Med. Chem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed