BDBM222334 (E)-5-(4-((diethylamino)methyl)-3-hydroxystyryl)-4-(hydroxymethyl)-2-methyl-pyridin-3-ol (7b)

SMILES CCN(CC)Cc1ccc(\C=C\c2cnc(C)c(O)c2CO)cc1O

InChI Key InChIKey=DHLQIQADZWXEQL-SOFGYWHQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222334   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sichuan University

LigandPNGBDBM222334((E)-5-(4-((diethylamino)methyl)-3-hydroxystyryl)-4...)
Affinity DataIC50:  2.33E+3nMAssay Description:For AChE or BuChE inhibition assays, a reaction mixture (100 mL) containing acetylthiocholine iodide (1 mmol/L, 30 mL) or butyrylthiocholine iodide (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sichuan University

LigandPNGBDBM222334((E)-5-(4-((diethylamino)methyl)-3-hydroxystyryl)-4...)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sichuan University

LigandPNGBDBM222334((E)-5-(4-((diethylamino)methyl)-3-hydroxystyryl)-4...)
Affinity DataIC50:  1.08E+4nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed