BDBM222342 (E)-2-((4-methylpiperazin-1-yl)methyl)-5-(2-(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)vinyl)phenol (8f)

SMILES CN1CCN(Cc2ccc(\C=C\c3cnc(C)c4OC(C)(C)OCc34)cc2O)CC1

InChI Key InChIKey=XPOLJBAQKKTERS-FNORWQNLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222342   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sichuan University

LigandPNGBDBM222342((E)-2-((4-methylpiperazin-1-yl)methyl)-5-(2-(2,2,8...)
Affinity DataIC50:  1.22E+4nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sichuan University

LigandPNGBDBM222342((E)-2-((4-methylpiperazin-1-yl)methyl)-5-(2-(2,2,8...)
Affinity DataIC50:  8.56E+4nMAssay Description:For AChE or BuChE inhibition assays, a reaction mixture (100 mL) containing acetylthiocholine iodide (1 mmol/L, 30 mL) or butyrylthiocholine iodide (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed