BDBM222350 IPR-1110 (1)

SMILES Cc1ccc(cc1Br)N1C(C(C(=O)c2ccc(Cl)cc2)=C(O)C1=O)c1cccc(F)c1

InChI Key InChIKey=FLCRMGKKLKMMAE-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 222350   

TargetUrokinase plasminogen activator surface receptor(Homo sapiens (Human))
Indiana University School of Medicine

LigandPNGBDBM222350(IPR-1110 (1))
Affinity DataKi:  700nM IC50:  1.84E+4nMAssay Description:Polarized fluorescence intensities were measured using an EnVision Multilabel plate reader (PerkinElmer) with excitation and emission wavelengths of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM222350(IPR-1110 (1))
Affinity DataKi:  700nMAssay Description:Inhibition of uPAR/uPA (unknown origin) interaction assessed as dissociation constant by fluorescence polarization (FP) assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM222350(IPR-1110 (1))
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of uPAR/uPA (unknown origin) interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed