BDBM224338 US10080750, Compound 15::US9321760, 15::US9662330, Compound 15
SMILES CN(C)CC(N1CCN(CC1)c1ncnc(N)c1-c1ccc(F)cc1)c1ccc(cc1)C(F)(F)F
InChI Key InChIKey=HYXXLNCSACYDRW-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 224338
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Emd Serono Research And Development Institute
Curated by ChEMBL
Emd Serono Research And Development Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair