BDBM224787 US9328120, 17::US9328120, 19 (enantiomer 2)

SMILES Cc1nnc(s1)[C@@H]1CC[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCC(F)(F)CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 224787   

TargetIsoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2)(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224787(US9328120, 17 | US9328120, 19 (enantiomer 2))
Affinity DataIC50:  1.35E+3nMT: 2°CAssay Description:The PDE9A2 enzymatic activity assay was run as scintillation proximity assay (SPA), in general according to the protocol of the manufacturer (GE Heal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE9A2 of High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A2)(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224787(US9328120, 17 | US9328120, 19 (enantiomer 2))
Affinity DataIC50:  16nMT: 2°CAssay Description:The PDE9A2 enzymatic activity assay was run as scintillation proximity assay (SPA), in general according to the protocol of the manufacturer (GE Heal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent