BDBM225747 hsp90_44

SMILES Oc1cc(O)c(cc1Cl)-n1c2ccc(CNS(=O)(=O)c3cccnc3)cc2[nH]c1=O

InChI Key InChIKey=CHDWYHGKXIQKTM-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 225747   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225747(hsp90_44)
Affinity DataIC50:  5.22nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
University Of Edinburgh

Curated by ChEMBL
LigandPNGBDBM225747(hsp90_44)
Affinity DataIC50:  5nMAssay Description:Inhibition of HSP90alpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225747(hsp90_44)
Affinity DataKd:  26.8nMAssay Description:ITCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225747(hsp90_44)
Affinity DataKd:  376nMAssay Description:Thermofluor AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed