BDBM22735 1,2-bis(3,4,5-trifluorophenyl)ethane-1,2-dione::Benzil-based compound, 13::CHEMBL193180
SMILES Fc1cc(cc(F)c1F)C(=O)C(=O)c1cc(F)c(F)c(F)c1
InChI Key InChIKey=FMFHXBPXDZLEKC-UHFFFAOYSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 22735
Affinity DataKi: 47.9nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 259nM ΔG°: -8.98kcal/molepH: 7.4 T: 2°CAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Inhibition of human intestinal carboxylesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 372nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
Affinity DataKi: 372nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:Inhibition of human carboxylesterase 1More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair