BDBM228618 BDBM50364365::US9345789, LI-2

SMILES CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@@H]1CCCN1C(C)=O

InChI Key InChIKey=QXSVKQKIGCAZOA-MLRMMBSGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228618   

TargetLegumain(Mus musculus)
Stanford University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM228618(BDBM50364365 | US9345789, LI-2)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University

US Patent
LigandPNGBDBM228618(BDBM50364365 | US9345789, LI-2)
Affinity DataIC50: >1.00E+6nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent