BDBM228618 BDBM50364365::US9345789, LI-2
SMILES CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@@H]1CCCN1C(C)=O
InChI Key InChIKey=QXSVKQKIGCAZOA-MLRMMBSGSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 228618
Affinity DataIC50: 8.30nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
The Board of Trustees of The Leland Stanford Junior University
US Patent
The Board of Trustees of The Leland Stanford Junior University
US Patent
Affinity DataIC50: >1.00E+6nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair