BDBM228654 (E)-4-(2-(4-chloro-3-nitrophenyl)) (C87)

SMILES [O-][N+](=O)c1cc(N\N=C2\C(=O)N(N=C2c2ccccc2)c2nc(cs2)-c2ccccc2)ccc1Cl

InChI Key InChIKey=VELQTEBILFDDQX-XAYXJRQQSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228654   

TargetTumor necrosis factor(Homo sapiens (Human))
Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

LigandPNGBDBM228654((E)-4-(2-(4-chloro-3-nitrophenyl)) (C87))
Affinity DataKd:  110nMpH: 7.0Assay Description:Surface plasmon resonance (SPR) assays were carried out on a BIAcore 3000 instrument (Biacore, Inc). Briefly, purified hTNFα was dissolved at 32...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed