BDBM22873 1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one::Bactil::CHEMBL305660::Ebastine::Kestine::NCGC00164603

SMILES CC(C)(C)c1ccc(cc1)C(=O)CCCN1CCC(CC1)OC(c1ccccc1)c1ccccc1

InChI Key InChIKey=MJJALKDDGIKVBE-UHFFFAOYSA-N

Data  1 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22873   

TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  45nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  61nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  1.10E+3nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM22873(1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piper...)
Affinity DataIC50:  47nMAssay Description:Compound is evaluated for in vitro receptor binding affinity against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed