BDBM22914 CHEMBL260374::N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide::Thioperamide::US11622967, Compound Thioperamide

SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1

InChI Key InChIKey=QKDDJDBFONZGBW-UHFFFAOYSA-N

Data  167 KI  14 IC50  1 Kd  11 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 22914   

TargetHrh3 protein(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 3A(GUINEA PIG)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  120nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSigma non-opioid intracellular receptor 1(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  180nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  2.80E+3nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2C adrenergic receptor(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  4.00E+3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M1(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  4.60E+3nMMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi:  6.40E+3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCholecystokinin receptor type A(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCholecystokinin receptor type A(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M2(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetD(1A) dopamine receptor(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlycine amidinotransferase, mitochondrial(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlycine receptor subunit alpha-1(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNischarin(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMelatonin receptor type 1B(Chick)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtachykinin-1(Homo sapiens (Human))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1D(RAT)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent serotonin transporter(GUINEA PIG)
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Vrije Universiteit

Curated by PDSP K_i Database

LigandBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI