BDBM230755 US9340537, 9::US9896444, Example 9
SMILES O[C@@H]1CCN(C1)c1ncc(cc1-c1nccs1)C(=O)Nc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=GTVNJIUBRIUDBD-CQSZACIVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 230755
Affinity DataIC50: 10nMAssay Description:Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The assay was performed by mixing 10 μL of the compound pre-diluted with 10 μL of ATP (20 μM ATP with 0.1 μCi [γ-33P]-ATP) with the...More data for this Ligand-Target Pair