BDBM230835 US9340537, 89::US9896444, Example 89
SMILES Cc1cc([nH]n1)-c1cc(cnc1N1CC(O)C1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1
InChI Key InChIKey=LMPOYJYSFOSTFK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 230835
Affinity DataIC50: 0.200nMAssay Description:Caliper ABL1 (64-515) Assay: The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Radio ABL1 (64-515) Assay: For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing...More data for this Ligand-Target Pair