BDBM231677 2-((4-Chlorophenoxy)methyl)-N-(2-sulfamoylethyl)thiazole-4-carboxamide (4c)

SMILES NS(=O)(=O)CCNC(=O)c1csc(COc2ccc(Cl)cc2)n1

InChI Key InChIKey=HRPBQFYVNIBGMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231677   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231677(2-((4-Chlorophenoxy)methyl)-N-(2-sulfamoylethyl)th...)
Affinity DataIC50:  2.60E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231677(2-((4-Chlorophenoxy)methyl)-N-(2-sulfamoylethyl)th...)
Affinity DataIC50:  190nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed