BDBM232923 US9346839, 4::US9738668, Compound 4
SMILES COC(=O)c1cc(ccc1O)[C@H](Nc1nc2ccc(OC)cc2s1)P(=O)(OC)OC
InChI Key InChIKey=UFYZZKPXXAXJHI-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 232923
Affinity DataKi: 5.50E+3nM ΔG°: -7.17kcal/mole IC50: 1.96E+4nM Kd: 496nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
Affinity DataKi: 5.50E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 ...More data for this Ligand-Target Pair
Affinity DataKi: 9.66E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Affinity DataKi: 9.66E+4nM ΔG°: -5.47kcal/mole IC50: 3.41E+5nM Kd: 496nMpH: 7.4 T: 2°CAssay Description:The interactions between compounds and ABAD were performed using the dual flow cell BIACORE 3000 instrument. Surface Plasmon Resonance (SPR) studies ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 ...More data for this Ligand-Target Pair
Affinity DataKd: 496nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Affinity DataKd: 496nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.41E+5nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair