BDBM233140 2-Nitrobenzohydrazide::Mr-I-179

SMILES NNC(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=YBBSKAGTEPBSNK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 233140   

TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

LigandPNGBDBM233140(2-Nitrobenzohydrazide | Mr-I-179)
Affinity DataIC50:  1.60E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM233140(2-Nitrobenzohydrazide | Mr-I-179)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human liver cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
University of Karachi

LigandPNGBDBM233140(2-Nitrobenzohydrazide | Mr-I-179)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM233140(2-Nitrobenzohydrazide | Mr-I-179)
Affinity DataIC50:  1.35E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed