BDBM23364 17-[2-(4-chlorophenyl)acetyl]-4,6-dimethoxy-11,17-diazatetracyclo[11.3.1.0^{2,11}.0^{3,8}]heptadeca-3(8),4,6-trien-12-one::Tetracyclic aza-amide, 9

SMILES COc1cc2CCN3C(C4CCCC(N4C(=O)Cc4ccc(Cl)cc4)C3=O)c2c(OC)c1

InChI Key InChIKey=BVPVUSPPHFLKMI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23364   

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Pfizer

LigandPNGBDBM23364(17-[2-(4-chlorophenyl)acetyl]-4,6-dimethoxy-11,17-...)
Affinity DataKi:  3.10E+3nM ΔG°:  -7.26kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed