BDBM23419 (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one::CHEMBL9352::Naringenin

SMILES Oc1ccc(cc1)[C@@H]1CC(=O)c2c(O)cc(O)cc2O1

InChI Key InChIKey=FTVWIRXFELQLPI-ZDUSSCGKSA-N

Data  9 KI  46 IC50  4 Kd  1 Other

PDB links: 22 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23419   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chonbuk National University

Curated by ChEMBL

LigandBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate pretreated for 10 mins followed by substrate addition measured after 20 mins by spectrop...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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