BDBM234207 US9359293, TH

SMILES CCCCCCC(=S)NCCCCC(NC(=O)Oc1ccccc1)C(=O)Nc1ccccc1

InChI Key InChIKey=JCABVKCNCPVTLU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 234207   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  310nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  120nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacylase sirtuin-6(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50:  1.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent