BDBM234335 Inhibitor A

SMILES ONC(=O)Cc1cc2ccccc2oc1=O

InChI Key InChIKey=AUFRSHPKGODFMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234335   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Huazhong University of Science and Technology

LigandPNGBDBM234335(Inhibitor A)
Affinity DataIC50:  537nMpH: 7.5 T: 2°CAssay Description:The MMP-9 assay was performed in 50 mM Tris-HCl buffer (pH 7.5, 10mM CaCl2, 150mM NaCl, 0.05% Brij-35). Then, 30ng Active MMP-9 was added to 50 μ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Huazhong University of Science and Technology

LigandPNGBDBM234335(Inhibitor A)
Affinity DataIC50:  175nMpH: 9.0 T: 2°CAssay Description:The TACE assay was carried out in 25 mM Tris-HCl buffer (pH 9, 2.5 μM ZnCl2 and 0.005% Brij-35). Then, 15ng TACE was added to buffer solution co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed