BDBM234335 Inhibitor A
SMILES ONC(=O)Cc1cc2ccccc2oc1=O
InChI Key InChIKey=AUFRSHPKGODFMN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 234335
Affinity DataIC50: 537nMpH: 7.5 T: 2°CAssay Description:The MMP-9 assay was performed in 50 mM Tris-HCl buffer (pH 7.5, 10mM CaCl2, 150mM NaCl, 0.05% Brij-35). Then, 30ng Active MMP-9 was added to 50 μ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Huazhong University of Science and Technology
Huazhong University of Science and Technology
Affinity DataIC50: 175nMpH: 9.0 T: 2°CAssay Description:The TACE assay was carried out in 25 mM Tris-HCl buffer (pH 9, 2.5 μM ZnCl2 and 0.005% Brij-35). Then, 15ng TACE was added to buffer solution co...More data for this Ligand-Target Pair