BDBM234975 4-(1-(2-bromo-6-fluorobenzyl)-1H-pyrazolo[4,3-b]pyridin-3-yl)-3-fluorobenzoic acid (1B)::US9556168, 1B

SMILES OC(=O)c1ccc(-c2nn(Cc3c(F)cccc3Br)c3cccnc23)c(F)c1

InChI Key InChIKey=VXCPJCUOCADWBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234975   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM234975(4-(1-(2-bromo-6-fluorobenzyl)-1H-pyrazolo[4,3-b]py...)
Affinity DataIC50:  2.29E+3nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent