BDBM23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO

InChI Key InChIKey=CEVLUPQNDFOYSI-UHFFFAOYSA-N

Data  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23500   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM23500(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Affinity DataIC50:  4.71E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM23500(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM23500(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM23500(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM23500(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Affinity DataIC50:  355nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM23500(4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)
Affinity DataIC50:  8.78E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed