BDBM235025 4-(1-(2-chloro-6-methylbenzyl)-4-fluoro-1H-indazol-3-yl)-5-fluoro-2-hydroxybenzoic acid (6A)::US9556168, 6A

SMILES Cc1cccc(Cl)c1Cn1nc(-c2cc(O)c(cc2F)C(O)=O)c2c(F)cccc12

InChI Key InChIKey=WMAJGLCGUMZZHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235025   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235025(4-(1-(2-chloro-6-methylbenzyl)-4-fluoro-1H-indazol...)
Affinity DataIC50:  24nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent